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Seth Lederman : ウィキペディア英語版 | Seth Lederman
Seth Lederman, MD is a physician,〔(【引用サイトリンク】url=http://investing.businessweek.com/research/stocks/private/person.asp?personId=112021597&privcapId=112008811&previousCapId=2520553&previousTitle=CAPNIA,%20Inc. )〕 scientist and specialty pharmaceuticals entrepreneur. He is a co-founder and the current President and Chairman〔(【引用サイトリンク】url=http://www.tonixpharma.com/content/about-tonix/board-of-directors.htm )〕 of Tonix Pharmaceuticals, a specialty pharmaceutical product development and commercialization company. ==Biography== Lederman earned his Bachelor's degree in Chemistry from Princeton University where he graduated ''cum laude'' in 1979.〔(【引用サイトリンク】url=http://asp.cumc.columbia.edu/facdb/profile_list.asp?uni=sl11&DepAffil=Medicine )〕 He completed his M.D. from Columbia University in 1983〔(【引用サイトリンク】url=http://www.columbia.edu/~sl11/ )〕 and continued his training at the Columbia Presbyterian Medical Center until 1986. Lederman co-founded and served as a managing partner of Konanda Pharma Partners and Konanda Pharma Fund I, LP, and its wholly owned operating companies, Validus and Fontus Pharmaceuticals Inc., which marketed Equetro (carbamazepine – Extended Release), Marplan (isocarboxazid) and Rocaltrol (calcitriol).〔 Dr. Lederman’s work on the CD40-Ligand (CD154) led to the development of therapeutic candidates for autoimmune diseases and organ transplant rejection in collaboration with Biogen-Idec and UCB/CellTech.〔 He also collaborated with Professor David Baltimore in identifying and functionally characterizing the CD40 signaling molecule, TRAF-3.〔(【引用サイトリンク】url=http://sethlederman.net/ )〕 Dr. Lederman’s “early work on HIV contributed to the understanding of how the V3 loop of HIV gp120 was involved in fusion with CD4 cell membranes, an early and essential event in viral entry and infection”.
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